The metastatic cells then journey through the circulatory system invading the vascular basement membrane and extracellular matrix in the process of extravasation. Once tumor cells acquire the ability to penetrate the surrounding tissues, the process of invasion is instigated as these motile cells pass through the basement membrane and extracellular matrix, progressing to intravasation as they penetrate the lymphatic or vascular circulation.

The course of tumor metastasis entails a series of stages that lead to the formation of secondary tumors in distant organs and is, largely, responsible for the mortality and morbidity of cancer. Universidad Nacional de Quilmes, 1998.Of primary importance in the prognosis of cancer patients is the sequence of events leading to the development of tumor cell invasion and metastasis. San Martín was allegedly part of the lodge, and he took the Maitland Plan as a blueprint for the movements necessary to defeat the Spanish army in South America he carried on successfully with the last five points of the plan, and thus liberated a great part of the continent. British military actions against Spanish South America ceased during the Peninsular War, when France turned against Spain and Britain allied itself with the Spanish resistance.Īccording to Argentine historians like Felipe Pigna and Rodolfo Terragno, José de San Martín, the Argentine general and prime leader of the southern part of South America's successful struggle for independence from the Spanish Empire, was introduced to the plan (during his stay in London in 1811) by members of the Logia Lautaro: a Freemasonic Lodge founded by Francisco de Miranda and Scottish Lord MacDuff ( James Duff, 4th Earl Fife). They attempted to seize Buenos Aires and Montevideo in 18, during the British invasions of the Río de la Plata, but were eventually defeated by the Spanish army and the local militias. The British tried to put the plan in practice twice and failed. Continue through sea and liberate Peru.Defeat the Spanish and take control of Chile.Coordinate actions with an independentist Chilean army.The Kingdom of Great Britain was by then at war with the Kingdom of Spain and the French First Republic in the Napoleonic Wars, and was seeking to expand its influence in South America since the loss of the Thirteen Colonies of North America, which had become independent some time before. The plan was titled Plan to capture Buenos Aires and Chile, and then emancipate Peru and Quito. Maitland Plan ( Spanish, Plan de Maitland), refers to a plan created by British Major General Thomas Maitland in 1800. 19th century British plan to capture Buenos Aires and Chile

Beyond Asimios- Part 2 by Martin Fossum